Puyo (Spanish Puyo) is a city in the central part of Ecuador, the administrative center of the Pastaza province. Located at an altitude of 953 m above sea level, on the Puyo River, 155 km from the country’s capital, the city of Quito.

The 2010 census reported that Puyo had a population of 24,881. The city was founded on May 12, 1899. In the town of Shell, 10 km northwest of Puyo, there is a small airport.